SCHEMBL22758987

SCHEMBL22758987

CC(C)[C@@H](CO)NC(=O)[C@@H]1CSSCCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)NC([C@@H](C)O)C(=O)N1

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 12/20 0.73
▸ SSTR4 P31391 12/20 0.73
▸ SSTR2 P30874 11/20 0.73
▸ SSTR3 P32745 8/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21090931 0.97 SSTR5 (0.78) SSTR5SSTR4SSTR2SSTR3
SCHEMBL18712336 0.97 SSTR5 (0.78) SSTR5SSTR4SSTR2SSTR3
SCHEMBL8262030 0.97 SSTR5 (0.78) SSTR5SSTR4SSTR2SSTR3
SCHEMBL18712350 0.97 SSTR5 (0.78) SSTR5SSTR4SSTR2SSTR3
SCHEMBL21099493 0.96 SSTR5 (0.77) SSTR5SSTR4SSTR2SSTR3
SCHEMBL20822442 0.91 SSTR5 (0.72) SSTR5SSTR4SSTR2SSTR3
SCHEMBL21892145 0.91 SSTR5 (0.68) SSTR5SSTR4SSTR2SSTR3
SCHEMBL22183423 0.90 SSTR2 (0.76) SSTR5SSTR4SSTR2SSTR3
SCHEMBL31476452 0.89 SSTR4 (0.80) SSTR5SSTR4SSTR2SSTR3
SCHEMBL21312757 0.89 SSTR5 (0.66) SSTR5SSTR4SSTR2SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11517581-B2 Zika virus protease inhibitors and methods of use thereof VERSITECH LIMITED (CN) 2022-12-06 — — US disclosed
US-20200384005-A1 ZIKA VIRUS PROTEASE INHIBITORS AND METHODS OF USE THEREOF FUNDACION UNIVERSITARIA SAN ANTONIO (ES) 2020-12-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517581-B2 Zika virus protease inhibitors and methods of use thereof CTRL, FURIN, SPINT2 SSTR5 4804/4885SSTR4 4737/4885SSTR2 4827/4885
US-20200384005-A1 ZIKA VIRUS PROTEASE INHIBITORS AND METHODS OF USE THEREOF CTRL, FURIN, SPINT2 SSTR5 4804/4885SSTR4 4737/4885SSTR2 4827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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