⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997310 | 0.85 | — | — | |
| SCHEMBL29916360 | 0.83 | TSHR (0.41) | — | |
| SCHEMBL19287199 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL10883734 | 0.78 | — | — | |
| SCHEMBL15911232 | 0.77 | — | — | |
| SCHEMBL28320256 | 0.77 | — | — | |
| SCHEMBL1153789 | 0.76 | — | — | |
| SCHEMBL745664 | 0.75 | — | — | |
| SCHEMBL5014072 | 0.74 | — | — | |
| SCHEMBL387295 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | claimed |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-29 | — | — | US | disclosed |
| US-20230129118-A1 | PHYTOSPHINGOSINE DERIVATIVES AS ADJUVANTS IN IMMUNE STIMULATION | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-04-27 | — | — | US | disclosed |
| WO-2020127508-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| EP-2245033-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-08-31 | — | — | EP | disclosed |
| US-8008298-B2 | Pyrrolopyrazine kinase inhibitors | Roche Palo Alto (US) | 2011-08-30 | — | — | US | disclosed |
| EP-2245033-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| US-20100267666-A1 | Pyrrolopyrazine kinase inhibitors | ROCHE PALO ALTO LLC | 2010-10-21 | — | — | US | disclosed |
| EP-1747883-B1 | Infrared-sensitive planographic printing plate precursor | FUJIFILM CORP (JP) | 2010-03-10 | — | — | EP | disclosed |
| WO-2009106441-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| US-6818378-B2 | SUITABLE FOR DIRECT PLATE-MAKING, WHICH IS CAPABLE OF PRODUCING A PRINTING PLATE DIRECTLY BY RECORDING DIGITAL IMAGE SIGNALS FORMED BY AND OUTPUT FROM COMPUTER WITH AN INFRARED LASER BEAM | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
| US-20030186163-A1 | Suitable for direct plate-making, which is capable of producing a printing plate directly by recording digital image signals formed by and output from computer with an infrared laser beam | FUJI PHOTO FILM CO., LTD. | 2003-10-02 | — | — | US | disclosed |
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |
| EP-0208145-B1 | HEARING AID WITH PIVOTABLE COVER | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4925879-A | ANTIDEPRESSANTS | BOOTS COMPANY, PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| US-4774161-A | LITHOGRAPHY, PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | disclosed |
| US-4741985-A | Light-sensitive composition comprising a diazonium salt condensate and a modified polyvinyl acetal polymer. | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0208145-A2 | Hearing aid with pivotable cover | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | disclosed |