Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 14/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 14/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276370 | 1.00 | CHRM4 (0.51) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2281724 | 0.94 | CHRM4 (0.47) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2281719 | 0.94 | CHRM4 (0.47) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2281470 | 0.92 | CHRM4 (0.43) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2281467 | 0.92 | CHRM4 (0.43) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2273568 | 0.90 | CHRM2 (0.41) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2273571 | 0.90 | CHRM2 (0.41) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2273942 | 0.86 | CHRM4 (0.42) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2273946 | 0.86 | CHRM4 (0.42) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2274873 | 0.85 | CHRM2 (0.35) | CHRM4CHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996189-B1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LTD (GB) | 2012-09-26 | — | — | EP | disclosed |
| US-20110207777-A1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | TELECOM IP LIMITED | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207777-A1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM5 4/4885CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.