Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15655314 | 0.82 | CD38 (0.37) | CDK2MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL25806590 | 0.81 | MKNK1 (0.38) | MKNK1MKNK2JAK2JAK1CD38 | |
| SCHEMBL22764057 | 0.81 | MKNK1 (0.38) | MKNK1MKNK2JAK2JAK1CD38 | |
| SCHEMBL26374101 | 0.80 | JAK2 (0.36) | MKNK1MKNK2JAK2JAK1CD38 | |
| SCHEMBL12182765 | 0.78 | CD38 (0.42) | CDK2MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL25806378 | 0.77 | PIK3CD (0.31) | JAK1IRAK4 | |
| SCHEMBL30822877 | 0.76 | IRAK4 (0.34) | CDK2MEN1KMT2AJAK2JAK1 | |
| SCHEMBL12183781 | 0.72 | CD38 (0.41) | CDK2MKNK1MKNK2CD38IRAK4 | |
| SCHEMBL14250456 | 0.70 | KMT2A (0.40) | MEN1KMT2AJAK2JAK1IDH1 | |
| SCHEMBL14250455 | 0.70 | KMT2A (0.40) | MEN1KMT2AJAK2JAK1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393492-A2 | METHOD FOR SYNTHESIZING FUROIMIDAZOPYRIDINE COMPOUND, POLYMORPHIC SUBSTANCE AND POLYMORPHIC SUBSTANCE OF SALT | Hangzhou Highlightll Pharmaceutical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2020244349-A1 | METHOD FOR SYNTHESIZING FUROIMIDAZOPYRIDINE COMPOUND, POLYMORPHIC SUBSTANCE AND POLYMORPHIC SUBSTANCE OF SALT | 广州高瓴制药有限公司 | 2020-12-10 | — | — | WO | disclosed |