SCHEMBL22767586

SCHEMBL22767586

N=CC[C@H]1CC[C@H](Nc2c(N)cnc3ccoc23)CO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22764179 0.86 IRAK4 (0.36) IRAK4
SCHEMBL20051452 0.83 PIK3CD (0.33) IRAK4
SCHEMBL21286839 0.83 PIK3CD (0.33) IRAK4
SCHEMBL20051455 0.83 PIK3CD (0.33) IRAK4
Hydrochloric Acid SCHEMBL31382910 0.82 PIK3CD (0.33) IRAK4
SCHEMBL20051446 0.75 IRAK4 (0.40) IRAK4
SCHEMBL22764057 0.74 MKNK1 (0.38) IRAK4
SCHEMBL20051777 0.72 IRAK4 (0.39) IRAK4
SCHEMBL21286732 0.72 IRAK4 (0.37) IRAK4
SCHEMBL30822849 0.72 IRAK4 (0.37) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393492-A2 METHOD FOR SYNTHESIZING FUROIMIDAZOPYRIDINE COMPOUND, POLYMORPHIC SUBSTANCE AND POLYMORPHIC SUBSTANCE OF SALT Hangzhou Highlightll Pharmaceutical Co., Ltd. (CN) 2024-07-03 EP disclosed
WO-2020244349-A1 METHOD FOR SYNTHESIZING FUROIMIDAZOPYRIDINE COMPOUND, POLYMORPHIC SUBSTANCE AND POLYMORPHIC SUBSTANCE OF SALT 广州高瓴制药有限公司 2020-12-10 WO disclosed