⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404065 | 1.00 | — | — | |
| SCHEMBL17037474 | 1.00 | — | — | |
| SCHEMBL6431779 | 0.85 | GBA1 (0.72) | — | |
| SCHEMBL6856714 | 0.85 | GBA1 (0.72) | — | |
| SCHEMBL20016401 | 0.85 | GBA1 (0.72) | — | |
| SCHEMBL7405332 | 0.82 | — | — | |
| SCHEMBL26452946 | 0.80 | GBA1 (0.44) | — | |
| SCHEMBL788564 | 0.80 | GBA1 (0.44) | — | |
| SCHEMBL29318343 | 0.78 | GBA1 (0.42) | — | |
| SCHEMBL7227000 | 0.78 | GBA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247496-A1 | 2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2020-12-10 | — | — | WO | disclosed |