Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.63 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.63 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300276 | 0.97 | TDP1 (0.68) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL23334534 | 0.97 | TDP1 (0.68) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL16123471 | 0.97 | TDP1 (0.68) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL30504309 | 0.95 | FOLH1 (0.70) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL8131388 | 0.94 | FOLH1 (0.71) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL13497879 | 0.93 | FOLH1 (0.76) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL12551857 | 0.93 | TDP1 (0.77) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL565248 | 0.93 | TDP1 (0.77) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL22975316 | 0.93 | TDP1 (0.77) | FOLH1TDP1PKMMEN1ABL1 | |
| SCHEMBL10171661 | 0.93 | TDP1 (0.77) | FOLH1TDP1PKMMEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020246602-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | 大塚製薬株式会社 | 2020-12-10 | — | — | WO | disclosed |