Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17114281 | 0.94 | NTRK1 (0.70) | NTRK1NTRK3 | |
| SCHEMBL17114035 | 0.90 | NTRK1 (0.72) | NTRK1NTRK3 | |
| SCHEMBL17114026 | 0.89 | NTRK1 (0.72) | NTRK1NTRK3 | |
| SCHEMBL18776375 | 0.89 | NTRK1 (0.72) | NTRK1NTRK3 | |
| SCHEMBL17113997 | 0.88 | NTRK1 (0.78) | NTRK1NTRK3 | |
| SCHEMBL17129775 | 0.87 | NTRK1 (0.81) | NTRK1 | |
| SCHEMBL17129707 | 0.87 | NTRK1 (0.81) | NTRK1 | |
| SCHEMBL18763096 | 0.87 | NTRK1 (0.70) | NTRK1NTRK3 | |
| SCHEMBL17114216 | 0.87 | NTRK1 (0.70) | NTRK1NTRK3 | |
| SCHEMBL17129778 | 0.87 | NTRK1 (0.69) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122345-B1 | TRKA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME (US) | 2020-12-16 | — | — | EP | disclosed |