Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112551 | 0.90 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL22772559 | 0.90 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL30112749 | 0.83 | GRIN1 (0.67) | GRIN1GRIN2B | |
| SCHEMBL22772473 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL22772543 | 0.79 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL30112578 | 0.79 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL28691028 | 0.79 | GRIN1 (0.90) | GRIN1GRIN2B | |
| SCHEMBL22772515 | 0.77 | GRIN2B (0.59) | GRIN1GRIN2B | |
| SCHEMBL29526515 | 0.77 | GRIN2B (0.59) | GRIN1GRIN2B | |
| SCHEMBL22772463 | 0.76 | GRIN2B (0.58) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459336-B2 | Pyrazine carbamates and their use as GluN2B receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-04 | — | — | US | disclosed |
| US-20200392155-A1 | PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392155-A1 | PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | GRIN2B, GRIN2A, GRIN2C | GRIN1 4/4885GRIN2B 1/4885 |
| US-11459336-B2 | Pyrazine carbamates and their use as GluN2B receptor modulators | GRIN2B, GRIN2A, GRIN2C | GRIN1 4/4885GRIN2B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.