Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249259 | 0.90 | HTR2A (0.67) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL31613081 | 0.90 | HTR2A (0.67) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL13900828 | 0.80 | HTR2A (0.56) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL16005849 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL12657296 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL18963265 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL18963321 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL15721675 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL16712664 | 0.78 | HTR2A (0.54) | HTR2ATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL22278135 | 0.78 | KDM4E (0.48) | HTR2ATAAR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10866236-B2 | Detection of cleavage activity of an enzyme | MOLOGIC LIMITED (GB) | 2020-12-15 | — | — | US | disclosed |