Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.84 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24659890 | 1.00 | PDCD1 (0.84) | PDCD1CD274 | |
| SCHEMBL24446638 | 0.96 | PDCD1 (0.79) | PDCD1CD274 | |
| SCHEMBL24446162 | 0.96 | PDCD1 (0.78) | PDCD1CD274 | |
| SCHEMBL22779896 | 0.95 | PDCD1 (0.80) | PDCD1CD274 | |
| SCHEMBL24660114 | 0.95 | PDCD1 (0.90) | PDCD1CD274 | |
| SCHEMBL24446613 | 0.95 | PDCD1 (0.77) | PDCD1CD274 | |
| SCHEMBL24446152 | 0.95 | PDCD1 (0.79) | PDCD1CD274 | |
| SCHEMBL24660088 | 0.93 | PDCD1 (0.74) | PDCD1CD274 | |
| SCHEMBL24446430 | 0.93 | PDCD1 (0.90) | PDCD1CD274 | |
| SCHEMBL24660092 | 0.93 | PDCD1 (0.92) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750887-A1 | BIARYL DERIVATIVE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |