Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.75 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22779897 | 0.91 | PDCD1 (0.75) | PDCD1CD274 | |
| SCHEMBL22779882 | 0.89 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL24446457 | 0.89 | PDCD1 (0.75) | PDCD1CD274 | |
| SCHEMBL22779994 | 0.88 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL24446126 | 0.88 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL22779821 | 0.88 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL22779886 | 0.86 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL22769826 | 0.86 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL24446477 | 0.86 | PDCD1 (0.93) | PDCD1CD274 | |
| SCHEMBL22779910 | 0.85 | PDCD1 (1.00) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750887-A1 | BIARYL DERIVATIVE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |