Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784221 | 0.92 | CHRM3 (0.57) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL21095697 | 0.92 | CHRM3 (0.58) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL22784237 | 0.87 | CHRM3 (0.68) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL23562324 | 0.86 | CHRM3 (0.64) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL23562419 | 0.86 | CHRM3 (0.64) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL23562279 | 0.86 | CHRM3 (0.64) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL30059407 | 0.86 | CHRM3 (0.64) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL30061460 | 0.86 | CHRM3 (0.64) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL25126221 | 0.86 | CHRM3 (0.61) | CHRM3KCNH2TRPM8CHRM2CHRM1 | |
| SCHEMBL25126854 | 0.86 | CHRM3 (0.61) | CHRM3KCNH2TRPM8CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239892-A1 | COMPOUNDS FOR MODULATION OF CD68 AND USES THEREOF | ARKUDA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2020252222-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2020-12-17 | — | — | WO | disclosed |