Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.49 |
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784237 | 0.85 | CHRM3 (0.68) | CHRM3KCNH2TRPM8TRPV1 | |
| SCHEMBL22784184 | 0.82 | CHRM3 (0.66) | CHRM3KCNH2TRPM8TRPV1 | |
| SCHEMBL22784549 | 0.82 | CHRM3 (0.53) | CHRM3KCNH2TRPM8TRPV1 | |
| SCHEMBL22784179 | 0.82 | CHRM3 (0.66) | CHRM3KCNH2TRPM8TRPV1 | |
| Hydrochloric Acid SCHEMBL29560765 | 0.81 | CHRM3 (0.65) | CHRM3KCNH2TRPM8TRPV1 | |
| SCHEMBL24516877 | 0.80 | CHRM3 (0.66) | CHRM3KCNH2TRPM8HHATCYP2D6 | |
| SCHEMBL29704874 | 0.80 | CHRM3 (0.66) | CHRM3KCNH2TRPM8HHATCYP2D6 | |
| SCHEMBL26966430 | 0.80 | CHRM3 (0.66) | CHRM3KCNH2TRPM8HHATCYP2D6 | |
| SCHEMBL22784481 | 0.80 | CHRM3 (0.58) | CHRM3KCNH2TRPM8HHATCYP2D6 | |
| SCHEMBL22784697 | 0.80 | CHRM3 (0.58) | CHRM3KCNH2TRPM8HHATCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252222-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2020-12-17 | — | — | WO | disclosed |