Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22785856 | 0.87 | TYR (0.58) | TYRPPARGPPARDPPARAKDM4E | |
| SCHEMBL22785844 | 0.81 | TYR (0.57) | TYRPPARGPPARDPPARAKDM4E | |
| SCHEMBL12798033 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL7153515 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL12604144 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL21245904 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL1782020 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL21245905 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL1782151 | 0.77 | GAA (0.50) | TYRGAAMAPT | |
| SCHEMBL22785853 | 0.77 | TYR (0.56) | TYRPPARGPPARDPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906969-A1 | ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF | East China University of Science and Technology (CN) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020249117-A1 | ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF | 华东理工大学 | 2020-12-17 | — | — | WO | disclosed |