Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 20/20 | 1.00 |
| ▸ | UBA3 | Q8TBC4 | 20/20 | 1.00 |
| ▸ | UBA1 | P22314 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787515 | 0.86 | NAE1 (0.75) | NAE1UBA3 | |
| SCHEMBL22787594 | 0.86 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL22787593 | 0.84 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL24286881 | 0.82 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL22787476 | 0.81 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL24286005 | 0.81 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL22787480 | 0.80 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL22787524 | 0.79 | NAE1 (0.71) | NAE1UBA3UBA1 | |
| SCHEMBL22787531 | 0.77 | NAE1 (0.67) | NAE1UBA3UBA1 | |
| SCHEMBL22787526 | 0.77 | NAE1 (0.67) | NAE1UBA3UBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985007-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249109-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-17 | — | — | WO | disclosed |