Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 18/20 | 0.60 |
| ▸ | UBA3 | Q8TBC4 | 18/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 14/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 14/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286895 | 1.00 | NAE1 (0.60) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787462 | 0.85 | NAE1 (0.60) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL24286186 | 0.84 | NAE1 (0.60) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787478 | 0.84 | NAE1 (0.61) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787564 | 0.82 | NAE1 (0.60) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL24286261 | 0.82 | NAE1 (0.56) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL24286192 | 0.80 | NAE1 (0.61) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787529 | 0.79 | NAE1 (0.51) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787567 | 0.79 | NAE1 (0.83) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787656 | 0.78 | NAE1 (0.53) | NAE1UBA3SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249109-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-17 | — | — | WO | disclosed |