Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23429787 | 0.85 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL29565934 | 0.85 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL22521404 | 0.85 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL27188768 | 0.85 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL21061526 | 0.85 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL21129820 | 0.83 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL22521591 | 0.83 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL22787756 | 0.82 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL21061459 | 0.79 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL23430001 | 0.79 | PRMT5 (0.38) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020250123-A1 | PRMT5 INHIBITORS | LUPIN LIMITED (IN) | 2020-12-17 | — | — | WO | disclosed |