Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 14/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.49 |
| ▸ | CDK2 | P24941 | 14/20 | 0.49 |
| ▸ | CDK7 | P50613 | 14/20 | 0.49 |
| ▸ | CCNH | P51946 | 14/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 14/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494812 | 1.00 | CCNK (0.49) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL31460656 | 1.00 | CCNK (0.49) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL29527460 | 1.00 | CCNK (0.49) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL28717093 | 1.00 | CCNK (0.49) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL889079 | 0.94 | USP30 (0.53) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL23003229 | 0.93 | CDK2 (0.50) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL23063687 | 0.93 | CDK2 (0.50) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL23003227 | 0.93 | CDK2 (0.50) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL23003217 | 0.89 | CCNA2 (0.60) | CCNKCCNA2CDK2CDK7CCNH | |
| SCHEMBL23003215 | 0.89 | CCNA2 (0.60) | CCNKCCNA2CDK2CDK7CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302877-A | Quinazolinyl compounds and methods of use | 基因泰克公司 | 2022-04-08 | — | — | CN | disclosed |
| WO-2020252165-A1 | QUINAZOLINYL COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2020-12-17 | — | — | WO | disclosed |