Terephthalamic Acid

Terephthalamic Acid

SCHEMBL227899

NC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.74
PARP15 Q460N3 2/20 0.74
TSHR P16473 4/20 0.71
TP53 P04637 1/20 0.71
CYP2C19 P33261 2/20 0.65
POLB P06746 1/20 0.65
CYP3A4 P08684 1/20 0.65
PARP1 P09874 1/20 0.65
MAPT P10636 1/20 0.65
RECQL P46063 1/20 0.65
BLM P54132 1/20 0.65
PMP22 Q01453 1/20 0.65
HSD17B10 Q99714 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
SRD5A2 P31213 2/20 0.60
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
CA12 O43570 3/20 0.57
CA9 Q16790 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL29077776 1.00 PARP10 (0.74) PARP10PARP15TSHRTP53CYP2C19
Terephthalamide SCHEMBL27396114 1.00 PARP10 (0.74) PARP10PARP15TSHRTP53CYP2C19
Terephthalamic Acid SCHEMBL6859681 0.97 PARP10 (0.71) PARP10PARP15TSHRTP53CYP2C19
Terephthalamic Acid SCHEMBL29054146 0.97 PARP10 (0.71) PARP10PARP15TSHRTP53CYP2C19
Terephthalamide SCHEMBL28689227 0.92 TSHR (0.80) PARP10PARP15TSHRTP53CYP2C19
SCHEMBL6500925 0.92 PARP15 (0.65) PARP10PARP15TSHRTP53CYP2C19
Terephthalamic Acid SCHEMBL16583862 0.92 PARP15 (0.65) PARP10PARP15TSHRTP53CYP2C19
Terephthalamic Acid SCHEMBL16583991 0.92 PARP10 (0.65) PARP10PARP15TSHRTP53CYP2C19
Terephthalic Acid SCHEMBL28758019 0.92 TSHR (0.80) PARP10PARP15TSHRTP53CYP2C19
Benzamide SCHEMBL11668267 0.89 TSHR (0.84) PARP10PARP15TSHRTP53CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198111-B1 LUBRICANT COMPOSITION INCLUDING CARBON NANOTUBES KYODO YUSHI (JP) 2025-11-26 EP claimed
US-12454655-B2 Lubricant composition comprising carbon nanotubes KYODO YUSHI CO., LTD. (JP) 2025-10-28 US claimed
EP-4630807-A1 METHOD FOR QUANTIFYING THE RECYCLED PET (RPET) CONTENT WITHIN A GIVEN PET CONTAINING PLASTIC MATERIAL Aarhus Universitet (DK) 2025-10-15 EP claimed
EP-4622953-A1 PREPARATION OF 4-CYANOBENZOYL CHLORIDES FROM ALKALI METAL 4-CARBAMOYL-BENZOATES BASF SE (DE) 2025-10-01 EP claimed
US-20250223255-A1 METHOD FOR PRODUCING ANILINE OR AN ANILINE-DERIVED PRODUCT COVESTRO DEUTSCHLAND AG (DE) 2025-07-10 US claimed
EP-4504691-A1 METHOD FOR PRODUCING ANILINE OR AN ANILINE-DERIVED PRODUCT Covestro Intellectual Property GmbH & Co. KG (DE) 2025-02-12 EP claimed
CN-118922398-A Process for preparing aniline or aniline derivatives 科思创德国股份有限公司 2024-11-08 CN claimed
CN-110088108-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-06-14 CN claimed
WO-2024121196-A1 METHOD FOR QUANTIFYING THE RECYCLED PET (RPET) CONTENT WITHIN A GIVEN PET CONTAINING PLASTIC MATERIAL AARHUS UNIVERSITET (DK) 2024-06-13 WO claimed
WO-2024110227-A1 PREPARATION OF 4-CYANOBENZOYL CHLORIDES FROM ALKALI METAL 4-CARBAMOYL-BENZOATES BASF SE (DE) 2024-05-30 WO claimed
EP-0604800-A1 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors Dr. Karl Thomae GmbH (DE) 1994-07-06 EP claimed
WO-1994010990-A1 INHIBITION OF TNF PRODUCTION BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1994-05-26 WO claimed
WO-1993021942-A2 USE OF MMP INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1993-11-11 WO claimed
WO-1992013831-A1 HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-08-20 WO claimed
EP-0498665-A1 Hydroxamic acids derivatives, process for their preparation and use thereof BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1992-08-12 EP claimed
US-4859558-A Composition with fatty acid bisamide powder developer FUJI XEROX CO., LTD. (JP) 1989-08-22 US claimed
US-4673728-A Process for the production of copolyamide from aromatic dicarboxylic acids, adipic acid and hexamethylene diamine BAYER AKTIENGESELLSCHAFT (DE) 1987-06-16 US claimed
US-4124704-A ANTIMICROBIAL RIKER LABORATORIES, INC. (US) 1978-11-07 US claimed
US-4110375-A INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-29 US claimed
US-4067993-A Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids RIKER LABORATORIES, INC. (US) 1978-01-10 US claimed