Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GYS1 | P13807 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791169 | 0.79 | NOTUM (0.36) | NOTUMGYS1CYP1A2P2RX7 | |
| SCHEMBL22791189 | 0.79 | NOTUM (0.36) | NOTUMGYS1CYP1A2P2RX7 | |
| SCHEMBL22791057 | 0.78 | NOTUM (0.35) | NOTUMGYS1CYP1A2 | |
| SCHEMBL22791319 | 0.76 | SLC6A4 (0.42) | NOTUMGYS1CYP1A2 | |
| SCHEMBL21786437 | 0.76 | NOTUM (0.38) | NOTUMGYS1CYP1A2 | |
| SCHEMBL21786499 | 0.75 | NOTUM (0.40) | NOTUMGYS1CYP1A2 | |
| SCHEMBL21786431 | 0.75 | NOTUM (0.40) | NOTUMGYS1CYP1A2 | |
| SCHEMBL22791263 | 0.75 | CA1 (0.41) | MAPTP2RX7ALDH1A1 | |
| SCHEMBL22791170 | 0.74 | SLC6A4 (0.39) | NOTUMGYS1CYP1A2 | |
| SCHEMBL22791240 | 0.74 | SLC6A4 (0.40) | MAPTTP53NOTUMGYS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392116-A1 | SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS | NORTHWESTERN UNIVERSITY (US) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392116-A1 | SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS | MYC, MYCBP, MYCBP2 | USP1 3940/4885WDR48 1255/4885MAPT 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.