Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776614 | 0.91 | PTGER4 (0.53) | PTGER4PTGER2PTGDR | |
| SCHEMBL22776466 | 0.91 | PTGER4 (0.53) | PTGER4PTGER2PTGDR | |
| SCHEMBL29527734 | 0.91 | PTGER4 (0.53) | PTGER4PTGER2PTGDR | |
| SCHEMBL22776910 | 0.83 | PDE2A (0.44) | PTGER4PTGER2PTGDR | |
| SCHEMBL29614474 | 0.83 | PDE2A (0.44) | PTGER4PTGER2PTGDR | |
| SCHEMBL22776912 | 0.83 | PDE2A (0.44) | PTGER4PTGER2PTGDR | |
| SCHEMBL22791346 | 0.81 | PTGER4 (0.55) | PTGER4PTGER2PTGDR | |
| SCHEMBL22791348 | 0.78 | PTGER4 (0.57) | PTGER4PTGER2PTGDR | |
| SCHEMBL22791351 | 0.78 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL22777394 | 0.75 | PTGER4 (0.59) | PTGER4PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |