Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279341 | 1.00 | PADI4 (0.53) | PADI4ABCG2BCHEKCNA3L3MBTL1 | |
| SCHEMBL2283091 | 0.92 | PADI4 (0.50) | PADI4ABCG2BCHEKCNA3L3MBTL1 | |
| SCHEMBL2283097 | 0.92 | PADI4 (0.50) | PADI4ABCG2BCHEKCNA3L3MBTL1 | |
| SCHEMBL2278731 | 0.89 | PADI4 (0.50) | PADI4ABCG2PPARGCYSLTR2KDM4E | |
| SCHEMBL2278736 | 0.89 | PADI4 (0.50) | PADI4ABCG2PPARGCYSLTR2KDM4E | |
| SCHEMBL2280088 | 0.81 | PADI4 (0.48) | PADI4ABCG2L3MBTL1LMNACYSLTR2 | |
| SCHEMBL2280086 | 0.81 | PADI4 (0.48) | PADI4ABCG2L3MBTL1LMNACYSLTR2 | |
| SCHEMBL2278507 | 0.80 | ABCG2 (0.50) | ABCG2BCHEKCNA3L3MBTL1PPARG | |
| SCHEMBL2278509 | 0.80 | ABCG2 (0.50) | ABCG2BCHEKCNA3L3MBTL1PPARG | |
| SCHEMBL2283908 | 0.78 | ABCG2 (0.47) | ABCG2BCHEL3MBTL1PPARGCYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |
| EP-1671948-A1 | CINNAMOYL COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-21 | — | — | EP | disclosed |