SCHEMBL2279513

SCHEMBL2279513

C1CNC(CC2CCCN2)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.43
MLNR O43193 1/20 0.43
ABCB11 O95342 1/20 0.43
EGFR P00533 1/20 0.43
FYN P06241 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
HTR1A P08908 1/20 0.43
CHRM5 P08912 1/20 0.43
ADRA2A P08913 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CHRM1 P11229 1/20 0.43
ADRA2B P18089 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577662 1.00 CYP2D6 (0.43) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL27663525 1.00 CYP2D6 (0.43) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL7918004 0.94 CYP2D6 (0.50) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL21568741 0.91 CYP2D6 (0.52) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL14083904 0.86
SCHEMBL29348041 0.84 CYP2D6 (0.38) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL20833451 0.84 CYP2D6 (0.42) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL26725697 0.84 CYP2D6 (0.42) CYP2D6MEN1ALDH1A1LMNATP53
SCHEMBL12807377 0.84 CYP2D6 (0.38) CYP2D6MEN1ALDH1A1LMNATP53
Hydrochloric Acid SCHEMBL1426135 0.82 CYP2D6 (0.36) CYP2D6MEN1ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103232491-A Preparation method of cyclic phosphoric acid UNIV HEBEI SCIENCE & TECH 2013-08-07 CN claimed
CN-101193867-A N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole libraries OSI PHARM INC (US) 2008-06-04 CN claimed
CN-104955985-A Etching solution, replenishment solution, and method for forming copper wiring MEC CO LTD 2015-09-30 CN disclosed
CN-102300844-B Sulfamoyl-phenyl-ureidobenzamidine derivatives as antimalarial agents 4SC AG 2015-03-11 CN disclosed
CN-101151244-B Histamine H3 receptor agents, preparation and therapeutic uses LILLY CO ELI 2014-09-03 CN disclosed
CN-101970572-B Photocurable composition SEKISUI CHEMICAL CO LTD 2014-01-29 CN disclosed
CN-1956952-B Histamine H3 receptor agents, preparation and therapeutic uses LILLY CO ELI 2013-12-11 CN disclosed
CN-103232491-A Preparation method of cyclic phosphoric acid UNIV HEBEI SCIENCE & TECH 2013-08-07 CN disclosed
CN-101263112-B Histamine H3 receptor agents, preparation and therapeutic uses LILLY CO ELI 2012-10-10 CN disclosed
CN-1960969-B Histamine H3 receptor agents, methods of preparation and therapeutic uses thereof LILLY CO ELI 2012-03-28 CN disclosed
US-8088368-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2012-01-03 US disclosed
CN-101151244-A Histamine H3 receptor agents, preparation and therapeutic uses LILLY CO ELI (US) 2008-03-26 CN disclosed
CN-100376557-C Quinoline derivatives as ligands for neuropeptide Y receptors HOFFMANN LA ROCHE (CH) 2008-03-26 CN disclosed
CN-101142180-A Pyrrolidine derivatives as histamine h3 receptor antagonists LILLY CO ELI (US) 2008-03-12 CN disclosed
CN-101006082-A Histamine H3 receptor agents, methods of preparation and therapeutic uses LILLY CO ELI (US) 2007-07-25 CN disclosed
CN-1960969-A Histamine H3 receptor agents, methods of preparation and therapeutic uses thereof LILLY CO ELI (US) 2007-05-09 CN disclosed
CN-1956952-A Histamine H3 receptor agents, preparation and therapeutic uses LILLY CO ELI (US) 2007-05-02 CN disclosed
CN-1522249-A Quinoline derivatives as ligands for neuropeptide Y receptors 2004-08-18 CN disclosed
CN-1501933-A Novel 10-cyclohexenylpyrrolobenzodiazepines * -3-carboxamides and derivatives thereof; tocolytic oxytocin receptor antagonists 2004-06-02 CN disclosed
CN-1166175-A Improved cyclic conjugated diene polymer and process for producing the same ASAHI K K K K (JP) 1997-11-26 CN disclosed