SCHEMBL22797227

SCHEMBL22797227

Clc1ccc2c(c1)C1(c3ccccc3-2)c2cc(-c3cccc(-c4ccccc4)c3)ccc2-c2ccc(-c3cccc(-c4ccccc4)c3)cc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.52
PGR P06401 1/20 0.43
CYP1A2 P05177 1/20 0.42
AKR1A1 P14550 1/20 0.41
AKR1B1 P15121 1/20 0.41
TDP2 O95551 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19383292 0.97 PDK2 (0.54) PDK2PGRCYP1A2AKR1A1AKR1B1
SCHEMBL29897946 0.92 PDK2 (0.59) PDK2PGRCYP1A2TDP2
SCHEMBL28854438 0.92 PDK2 (0.59) PDK2PGRCYP1A2TDP2
SCHEMBL20687375 0.91 PDK2 (0.48) PDK2PGRCYP1A2AKR1A1AKR1B1
SCHEMBL22797621 0.91 PDK2 (0.45) PDK2PGRAKR1A1AKR1B1TDP2
SCHEMBL30709020 0.90 PDK2 (0.62) PDK2PGRTDP2
SCHEMBL30709033 0.90 PDK2 (0.62) PDK2PGRTDP2
SCHEMBL25124898 0.89 PDK2 (0.64) PDK2PGRTDP2
SCHEMBL12362798 0.89 PDK2 (0.62) PDK2CYP1A2TDP2
SCHEMBL25068226 0.88 PDK2 (0.43) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed