SCHEMBL22797329

SCHEMBL22797329

Cc1ccc2c(c1)CCc1cc(C)ccc1C21c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.41
PDK2 Q15119 4/20 0.41
AKR1A1 P14550 1/20 0.38
AKR1B1 P15121 1/20 0.38
SIGMAR1 Q99720 3/20 0.36
DRD2 P14416 3/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
DRD1 P21728 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
DRD4 P21917 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22799449 0.97 PARP1 (0.40) PARP1PDK2AKR1A1AKR1B1SIGMAR1
SCHEMBL20121806 0.87 PDK2 (0.49) PDK2AKR1A1AKR1B1
SCHEMBL22799413 0.85 PDK2 (0.47) PDK2AKR1A1AKR1B1SIGMAR1DRD2
SCHEMBL22797225 0.84 PDK2 (0.39) PARP1PDK2SIGMAR1DRD2DRD4
SCHEMBL22797336 0.84 PDK2 (0.43) PDK2AKR1A1AKR1B1SIGMAR1DRD2
SCHEMBL22797700 0.82 PDK2 (0.42) PDK2AKR1A1AKR1B1RAB9A
SCHEMBL22799395 0.80 PDK2 (0.41) PDK2AKR1A1AKR1B1SIGMAR1DRD2
SCHEMBL19147675 0.80 PDK2 (0.58) PDK2AKR1A1AKR1B1KDM4EMAPT
SCHEMBL22797228 0.79 PDK2 (0.51) PARP1PDK2AKR1A1AKR1B1SIGMAR1
SCHEMBL22797608 0.79 PDK2 (0.38) PDK2AKR1A1AKR1B1SIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed