Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797851 | 0.86 | TACR1 (0.36) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27176078 | 0.84 | TACR1 (0.37) | TACR1SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL22797903 | 0.81 | SLC6A2 (0.35) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20596703 | 0.80 | TACR1 (0.40) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22449324 | 0.77 | SLC6A2 (0.39) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22797956 | 0.77 | TACR1 (0.39) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22797936 | 0.77 | SLC6A4 (0.41) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22797962 | 0.77 | SLC6A2 (0.36) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22798150 | 0.77 | TACR1 (0.32) | TACR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22797790 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822262-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2024-03-27 | — | — | EP | disclosed |
| EP-3822262-A1 | MUSCARINIC AGONISTS | Heptares Therapeutics Limited (GB) | 2021-05-19 | — | — | EP | disclosed |
| EP-3331869-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2020-12-23 | — | — | EP | disclosed |