SCHEMBL22797906

SCHEMBL22797906

CC1CN(CC(=O)N2CCc3ccc(OC(F)(F)F)cc32)CCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XIAP P98170 19/20 1.00
BIRC2 Q13490 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15837647 1.00 XIAP (1.00) XIAPBIRC2
Hydrochloric Acid SCHEMBL15811983 0.99 XIAP (0.98) XIAPBIRC2
Hydrochloric Acid SCHEMBL30701332 0.99 XIAP (0.98) XIAPBIRC2
Hydrochloric Acid SCHEMBL15811981 0.99 XIAP (0.98) XIAPBIRC2
SCHEMBL15841254 0.88 BIRC2 (1.00) XIAPBIRC2
SCHEMBL17160774 0.88 BIRC2 (1.00) XIAPBIRC2
SCHEMBL15837643 0.85 XIAP (1.00) XIAPBIRC2
SCHEMBL17160784 0.85 XIAP (1.00) XIAPBIRC2
SCHEMBL17160775 0.83 XIAP (1.00) XIAPBIRC2
SCHEMBL15837634 0.83 XIAP (1.00) XIAPBIRC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699562-B1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY ASTEX THERAPEUTICS LTD (GB) 2020-12-23 EP claimed