Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797770 | 0.92 | SCN9A (0.75) | SCN9AMAPTGSK3BALDH1A1KDM4E | |
| SCHEMBL22798278 | 0.91 | SCN9A (0.61) | SCN9AMAPTGSK3BALDH1A1KDM4E | |
| SCHEMBL22798280 | 0.91 | SCN9A (0.61) | SCN9AMAPTGSK3BALDH1A1KDM4E | |
| SCHEMBL22797828 | 0.90 | SCN9A (0.60) | SCN9AMAPTGSK3B | |
| SCHEMBL22797825 | 0.90 | SCN9A (0.60) | SCN9AMAPTGSK3B | |
| SCHEMBL23954505 | 0.88 | SCN9A (0.57) | SCN9AMAPTGSK3BALDH1A1KDM4E | |
| SCHEMBL20595175 | 0.86 | SCN9A (0.64) | SCN9AALDH1A1KDM4EMRGPRX4ACACB | |
| SCHEMBL20595176 | 0.86 | SCN9A (0.64) | SCN9AALDH1A1KDM4EMRGPRX4ACACB | |
| SCHEMBL22797745 | 0.83 | SCN9A (0.82) | SCN9AMAPTGSK3BALDH1A1MRGPRX4 | |
| SCHEMBL30450684 | 0.83 | SCN9A (0.82) | SCN9AMAPTGSK3BALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | claimed |
| CN-110612285-A | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2019-12-24 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-110612285-A | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2019-12-24 | — | — | CN | disclosed |