Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | CMA1 | P23946 | 3/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798276 | 1.00 | MALT1 (0.50) | MALT1EPHA2ELANECMA1XIAP | |
| SCHEMBL20484548 | 1.00 | MALT1 (0.50) | MALT1EPHA2ELANECMA1XIAP | |
| SCHEMBL20484552 | 0.97 | MALT1 (0.52) | MALT1EPHA2ELANECMA1XIAP | |
| SCHEMBL22798205 | 0.97 | MALT1 (0.52) | MALT1EPHA2ELANECMA1XIAP | |
| SCHEMBL20484549 | 0.97 | MALT1 (0.52) | MALT1EPHA2ELANECMA1XIAP | |
| SCHEMBL20484554 | 0.97 | MALT1 (0.52) | MALT1EPHA2ELANECMA1XIAP | |
| Trifluoroacetic Acid SCHEMBL20484535 | 0.93 | MALT1 (0.49) | MALT1EPHA2ELANECMA1CTSG | |
| Trifluoroacetic Acid SCHEMBL20484536 | 0.93 | MALT1 (0.49) | MALT1EPHA2ELANECMA1CTSG | |
| Trifluoroacetic Acid SCHEMBL20484532 | 0.93 | MALT1 (0.49) | MALT1EPHA2ELANECMA1CTSG | |
| SCHEMBL22798227 | 0.90 | MALT1 (0.51) | MALT1EPHA2ELANEXIAPCTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |