Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 9/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586362 | 1.00 | TAAR1 (0.48) | TAAR1ACEACE2PREPMEN1 | |
| SCHEMBL18620796 | 0.90 | TAAR1 (0.47) | TAAR1ACEPREPCMA1 | |
| SCHEMBL22811094 | 0.90 | ACE (0.54) | ACEACE2PREPTSHR | |
| SCHEMBL18619658 | 0.88 | PREP (0.51) | TAAR1ACEACE2PREPMEN1 | |
| SCHEMBL20484650 | 0.88 | PREP (0.51) | TAAR1ACEACE2PREPMEN1 | |
| SCHEMBL18619558 | 0.85 | ACE (0.62) | ACEACE2PREPMEN1KMT2A | |
| SCHEMBL20485168 | 0.85 | ACE (0.62) | ACEACE2PREPMEN1KMT2A | |
| SCHEMBL20485127 | 0.85 | MEN1 (0.51) | TAAR1ACEACE2PREPMEN1 | |
| SCHEMBL18619656 | 0.85 | MEN1 (0.51) | TAAR1ACEACE2PREPMEN1 | |
| SCHEMBL20484748 | 0.85 | ACE (0.50) | TAAR1ACEACE2PREPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |