Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | GSK3B | P49841 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798215 | 1.00 | SCN9A (0.77) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL23954506 | 0.89 | SCN9A (0.71) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL22798299 | 0.89 | SCN9A (0.61) | SCN9AMAPTGSK3B | |
| SCHEMBL23926194 | 0.89 | SCN9A (0.61) | SCN9AMAPTGSK3B | |
| SCHEMBL22798423 | 0.88 | SCN9A (0.78) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL23926191 | 0.88 | SCN9A (0.78) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL22797785 | 0.87 | SCN9A (1.00) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL20595170 | 0.86 | SCN9A (0.95) | SCN9AMAPTGSK3BSMN1; SMN2PPARG | |
| SCHEMBL22797770 | 0.83 | SCN9A (0.75) | SCN9AMAPTGSK3BSMN1; SMN2KDM4E | |
| SCHEMBL22797813 | 0.80 | SCN9A (0.73) | SCN9AMAPTGSK3BSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | claimed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |