Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984448 | 0.96 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1984447 | 0.96 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1914340 | 0.82 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL1980791 | 0.80 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL23247405 | 0.79 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL23247492 | 0.78 | HCRTR1 (0.31) | HCRTR1HCRTR2JAK3 | |
| SCHEMBL23247584 | 0.78 | JAK3 (0.35) | JAK3 | |
| SCHEMBL1914368 | 0.73 | JAK3 (0.33) | JAK3 | |
| SCHEMBL16766968 | 0.72 | CDC7 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL16766294 | 0.72 | CDC7 (0.33) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071203-B1 | TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-12-23 | — | — | EP | disclosed |