Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | GCG | P01275 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798208 | 0.83 | SCN9A (0.49) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL22797814 | 0.81 | SCN9A (0.51) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL30450047 | 0.81 | SCN9A (0.51) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL22799399 | 0.81 | SCN9A (0.49) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL20595193 | 0.81 | SCN9A (0.63) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL20595163 | 0.80 | SCN9A (0.49) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL22798253 | 0.78 | SCN9A (0.48) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL22809603 | 0.75 | SCN9A (0.46) | SCN9ASCN10AGCGSCN7AKCNH2 | |
| SCHEMBL28354796 | 0.74 | SCN9A (0.48) | SCN9ASCN10ASCN7AKCNH2SCN5A | |
| SCHEMBL22798297 | 0.73 | SCN9A (0.50) | SCN9ASCN10AGCGSCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | claimed |