Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22800873 | 0.96 | JAK3 (0.33) | KDM4ETSHRJAK3BTKCYP1A2 | |
| SCHEMBL22799653 | 0.85 | KDM4E (0.32) | KDM4ESLC37A4CAPN1 | |
| SCHEMBL22800303 | 0.83 | FNTA (0.35) | KDM4ESLC37A4CAPN1ALDH1A1 | |
| SCHEMBL22800875 | 0.81 | JAK3 (0.37) | JAK3BTKCAPN1 | |
| SCHEMBL22800181 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL22800283 | 0.79 | FNTA (0.34) | KDM4EJAK3BTKCAPN1ALDH1A1 | |
| SCHEMBL22800179 | 0.79 | KDM4E (0.43) | EDNRAKDM4EALDH1A1 | |
| SCHEMBL22800990 | 0.78 | FNTA (0.35) | KDM4E | |
| SCHEMBL22800170 | 0.76 | KDM4E (0.43) | KDM4ETSHRHCRTR1ALDH1A1 | |
| SCHEMBL22800180 | 0.75 | KDM4E (0.44) | EDNRAKDM4ESLC37A4ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | Knobbe, Martens, Olson & Bear, LLP | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN2, CAPN1 | EDNRA 1847/4885KDM4E 1957/4885TSHR 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.