Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775796 | 0.98 | GRIN2B (0.70) | GRIN2BGRIN1 | |
| SCHEMBL29550327 | 0.98 | GRIN2B (0.70) | GRIN2BGRIN1 | |
| SCHEMBL22775229 | 0.89 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL22775593 | 0.89 | GRIN2B (0.71) | GRIN2BGRIN1 | |
| SCHEMBL29550616 | 0.89 | GRIN2B (0.64) | GRIN2BGRIN1 | |
| SCHEMBL22775311 | 0.89 | GRIN2B (0.64) | GRIN2BGRIN1 | |
| SCHEMBL22775791 | 0.88 | GRIN2B (0.72) | GRIN2BGRIN1 | |
| SCHEMBL22774980 | 0.86 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL22775530 | 0.85 | GRIN2B (0.58) | GRIN2BGRIN1 | |
| SCHEMBL22775653 | 0.85 | GRIN2B (0.65) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249792-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |