Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025902 | 0.97 | EGFR (0.81) | EGFR | |
| SCHEMBL28531463 | 0.95 | EGFR (0.71) | EGFR | |
| SCHEMBL24204763 | 0.95 | EGFR (0.70) | EGFR | |
| SCHEMBL29117520 | 0.94 | EGFR (0.70) | EGFR | |
| SCHEMBL28536163 | 0.94 | EGFR (0.71) | EGFR | |
| SCHEMBL28530838 | 0.94 | EGFR (0.72) | EGFR | |
| SCHEMBL28536305 | 0.94 | EGFR (0.71) | EGFR | |
| SCHEMBL28908519 | 0.93 | EGFR (0.68) | EGFR | |
| SCHEMBL28529293 | 0.93 | EGFR (0.71) | EGFR | |
| SCHEMBL24780459 | 0.93 | EGFR (0.69) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |