Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804687 | 1.00 | MAOB (0.62) | MAOBNR1H4NR4A2MRGPRX4PTPRC | |
| SCHEMBL22804950 | 0.86 | NR4A2 (0.59) | MAOBNR4A2SMN1; SMN2RAB9A | |
| SCHEMBL22804948 | 0.86 | NR4A2 (0.59) | MAOBNR4A2SMN1; SMN2RAB9A | |
| SCHEMBL22804742 | 0.85 | MAOB (0.58) | MAOBNR1H4NR4A2PTPRCPTPN1 | |
| SCHEMBL22804739 | 0.85 | MAOB (0.58) | MAOBNR1H4NR4A2PTPRCPTPN1 | |
| SCHEMBL27488702 | 0.80 | MAOB (0.71) | MAOBNR1H4NR4A2MRGPRX4PTPRC | |
| SCHEMBL13951781 | 0.80 | MAOB (0.78) | MAOBNR1H4NR4A2MRGPRX4PTPRC | |
| SCHEMBL22804483 | 0.79 | MAOB (0.64) | MAOBNR1H4NR4A2MRGPRX4PTPRC | |
| SCHEMBL22805064 | 0.78 | NR4A2 (0.46) | MAOBNR1H4NR4A2SMN1; SMN2RXRA | |
| SCHEMBL22805565 | 0.78 | NR4A2 (0.62) | MAOBNR4A2MRGPRX4PTPRCPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254490-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-24 | — | — | WO | disclosed |