SCHEMBL2280495

SCHEMBL2280495

CC(=O)CC(=O)Nc1cc(NC(=O)CC(C)=O)cc(S(=O)(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA4 P22748 1/20 0.54
CA7 P43166 1/20 0.54
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
MAPT P10636 2/20 0.45
ACP1 P24666 5/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.39
NR4A1 P22736 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15215515 0.84 KMT2A (0.58) CA1CA2CA4CA7KDM4E
SCHEMBL5705537 0.83 CA1 (0.57) CA1CA2CA4CA7KDM4E
SCHEMBL2220428 0.82 CA1 (0.73) CA1CA2CA4CA7KDM4E
SCHEMBL7074703 0.81 CA1 (0.71) CA1CA2CA4CA7KDM4E
SCHEMBL6555677 0.81 CA1 (0.71) CA1CA2CA4CA7KDM4E
Potassium SCHEMBL29819348 0.81 CA1 (0.71) CA1CA2CA4CA7KDM4E
SCHEMBL9311514 0.79 CA1 (0.45) CA1CA2CA4CA7CYP1A2
SCHEMBL11335884 0.79 MEN1 (0.68) CA1CA2CA4CA7KDM4E
SCHEMBL11585233 0.78 CA1 (0.50) CA1CA2CA4CA7KDM4E
SCHEMBL10792985 0.77 PRMT1 (0.71) CA1CA2CA4CA7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-7115224-B2 Process for making acid dye stain-resistant fibers PRISMA FIBERS, INC. (US) 2006-10-03 US disclosed
US-6861480-B2 Yarn-forming composition of polyamide and sulfonated acid dye disabler PRISMA FIBERS, INC. (US) 2005-03-01 US disclosed
US-20040154110-A1 Stain-resistant polyamide composition and fibers UNIVERSAL FIBERS, INC. 2004-08-12 US disclosed
US-20040152840-A1 Stain resistant polyamide composition and fibers and method of production thereof PREMIERE FIBERS, INC. 2004-08-05 US disclosed
US-6753385-B2 A REAGENT ASSOCIATES WITH FREE ACID DYE SITES IN A POLYAMIDE; TEXTILE AND CARPET YARNS PRISMA FIBERS, INC. 2004-06-22 US disclosed
US-20040046279-A1 Stain-resistant polyamide composition and fibers and method of production thereof UNIVERSAL FIBERS, INC. 2004-03-11 US disclosed
US-6635346-B2 Polyamide containing acid dye PRISMA FIBERS, INC. 2003-10-21 US disclosed
US-20030138625-A1 Stain-resistant polyamide composition and fibers UNIVERSAL FIBERS, INC. 2003-07-24 US disclosed
US-6537475-B1 Stain resistant fiber forming yarn; melt extruding, disabling free acid dye sites and removing volatiles; spinning and drawing PRISMA FIBERS, INC. 2003-03-25 US disclosed
US-20020155288-A1 Stain-resistant polyamide composition and fibers and method of production thereof UNIVERSAL FIBERS, INC. 2002-10-24 US disclosed
US-6420044-B1 SULFOISOPHTHALIC ACID SALTS; CARRIER IS TERPOLYMER OF AN ALPHA-MONOOLEFIN, AN A,B-UNSATURATED CARBOXYLIC ACID ESTER AND AN INTERNAL ANHYDRIDE OF AN ETHYLENICALLY UNSATURATED CARBOXYLIC ACID; ACID DYES PRISMA FIBERS, INC. 2002-07-16 US disclosed
US-6117550-A CONTAINING AN ALKAL METAL, ALKALINE EARTH METAL OR TRANSITION METAL SALT OF 5-SULFOISOPHTHALIC ACID AND A POLYMERIC BLENDS PRISMA FIBERS, INC. (US) 2000-09-12 US disclosed
WO-1997007962-A1 STAIN-RESISTANT POLYAMIDE COMPOSITION AND FIBERS COOKSON FIBERS, INC., a subsidiary of COOKSON PLC (US) 1997-03-06 WO disclosed