Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.66 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22805623 | 0.91 | TLR8 (0.71) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL22826036 | 0.89 | TLR8 (0.65) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL29492937 | 0.89 | TLR8 (0.65) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL24384588 | 0.89 | TLR8 (0.65) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL24384575 | 0.88 | TLR8 (0.64) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL21325824 | 0.88 | TLR8 (0.64) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL22806213 | 0.84 | TLR8 (0.73) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL24384697 | 0.84 | KCNH2 (0.85) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL21325638 | 0.84 | KCNH2 (0.85) | TLR8TLR7KCNH2CYP2D6DRD1 | |
| SCHEMBL24384557 | 0.83 | KCNH2 (0.85) | TLR8TLR7KCNH2CYP2D6DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255039-A1 | COMBINATION OF HEPATITIS B VIRUS (HBV) VACCINES AND QUINAZOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-24 | — | — | WO | disclosed |