SCHEMBL2280663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12373819	0.89	S1PR1 (0.49)	S1PR1S1PR3ALDH1A1PGRCCR2
	SCHEMBL12373895	0.89	S1PR1 (0.44)	S1PR1S1PR3ALDH1A1CCR2LMNA
	SCHEMBL2279140	0.87	S1PR1 (0.47)	S1PR1S1PR3PGRCCR2CNR1
	SCHEMBL2388321	0.86	S1PR1 (0.60)	S1PR1S1PR3ALDH1A1PKMTSHR
	SCHEMBL12373808	0.86	S1PR1 (0.44)	S1PR1S1PR3PGRCCR2CNR1
	SCHEMBL2278598	0.86	S1PR1 (0.44)	S1PR1S1PR3ALDH1A1PGRCCR2
	SCHEMBL12373822	0.84	S1PR1 (0.46)	S1PR1S1PR3PGRCNR1PPARG
	SCHEMBL12373790	0.84	S1PR1 (0.52)	S1PR1S1PR3ALDH1A1PGRCCR2
	SCHEMBL12373817	0.84	CNR1 (0.51)	S1PR1S1PR3ALDH1A1PGRCCR2
	SCHEMBL2279361	0.84	S1PR1 (0.51)	S1PR1S1PR3CCR2CNR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.