Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.67 |
| ▸ | EML4 | Q9HC35 | 7/20 | 0.67 |
| ▸ | INSR | P06213 | 2/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
| ▸ | ROS1 | P08922 | 1/20 | 0.65 |
| ▸ | FER | P16591 | 1/20 | 0.65 |
| ▸ | LTK | P29376 | 1/20 | 0.65 |
| ▸ | BLK | P51451 | 1/20 | 0.65 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.65 |
| ▸ | BTK | Q06187 | 1/20 | 0.65 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.65 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.65 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.65 |
| ▸ | IGF1R | P08069 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22806726 | 0.94 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL29624110 | 0.94 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL23462678 | 0.89 | EGFR (0.69) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL29624140 | 0.88 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL22806791 | 0.88 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL30223083 | 0.88 | EGFR (0.73) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL23462680 | 0.88 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL23462666 | 0.87 | EGFR (0.67) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL30942591 | 0.87 | EGFR (0.80) | EGFRALKEML4INSRERBB2 | |
| SCHEMBL27237907 | 0.87 | EGFR (0.80) | EGFRALKEML4INSRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020256477-A1 | PYRIMIDINE DERIVATIVE INHIBITING GROWTH OF CANCER CELL AND MEDICINAL USE THEREOF | 주식회사 온코빅스 | 2020-12-24 | — | — | WO | claimed |