Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.54 |
| ▸ | TDO2 | P48775 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806698 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17740992 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17762843 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17741009 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17741159 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17741156 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17741161 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17729231 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL18806765 | 1.00 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL17747174 | 0.90 | IDO1 (0.52) | IDO1TDO2CYP2C9CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215153-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2020-12-23 | — | — | EP | disclosed |