Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18785056 | 0.80 | ALOX5AP (0.39) | ALDH1A1NPSR1L3MBTL1KDM4EALOX5AP | |
| SCHEMBL4730316 | 0.78 | CBFB (0.50) | CBFBMAPTGRM5KMT2ATGFBR1 | |
| SCHEMBL18785043 | 0.78 | CYP4F2 (0.41) | KDM4EHPGD | |
| SCHEMBL28261462 | 0.77 | CBFB (0.42) | CBFBMAPTGRM5KMT2ATGFBR1 | |
| SCHEMBL28163157 | 0.76 | GRM5 (0.48) | CBFBGRM5TGFBR1KDM4EHPGD | |
| SCHEMBL20628042 | 0.76 | KDM4E (0.42) | MAPTALDH1A1LMNAATMNPSR1 | |
| SCHEMBL14116546 | 0.75 | MPL (0.55) | CBFBMAPTGRM5KMT2ATGFBR1 | |
| SCHEMBL6301360 | 0.75 | CBFB (0.50) | CBFBMAPTGRM5KMT2ATGFBR1 | |
| SCHEMBL1206412 | 0.75 | CBFB (0.50) | CBFBMAPTGRM5KMT2ATGFBR1 | |
| SCHEMBL28209756 | 0.75 | CBFB (0.50) | CBFBGRM5TGFBR1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366674-B1 | PYRIDINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-106715428-A | Pesticidally active tetracyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-05-24 | — | — | CN | disclosed |