⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071355 | 0.72 | — | — | |
| SCHEMBL21397499 | 0.71 | — | — | |
| SCHEMBL26527714 | 0.69 | — | — | |
| SCHEMBL21499692 | 0.69 | — | — | |
| SCHEMBL24731094 | 0.68 | — | — | |
| SCHEMBL24894997 | 0.68 | — | — | |
| SCHEMBL21375644 | 0.68 | — | — | |
| SCHEMBL22890915 | 0.67 | — | — | |
| SCHEMBL12861943 | 0.67 | — | — | |
| SCHEMBL23287636 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541792-B1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |