Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | CTRC | Q99895 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18620799 | 0.91 | CMA1 (0.52) | CMA1TAAR1PREPACEGAA | |
| SCHEMBL22209501 | 0.88 | TAAR1 (0.49) | TAAR1PREPACEGAANPC1 | |
| SCHEMBL18619644 | 0.88 | TAAR1 (0.49) | TAAR1PREPACEGAANPC1 | |
| SCHEMBL18621642 | 0.88 | TAAR1 (0.49) | CMA1TAAR1PREPACENPC1 | |
| SCHEMBL22209497 | 0.88 | TAAR1 (0.49) | CMA1TAAR1PREPACENPC1 | |
| SCHEMBL22209426 | 0.87 | ACE (0.57) | TAAR1PREPACENPC1ELANE | |
| SCHEMBL18620607 | 0.87 | ACE (0.57) | TAAR1PREPACENPC1ELANE | |
| SCHEMBL18620796 | 0.85 | TAAR1 (0.47) | CMA1TAAR1PREPACENPC1 | |
| SCHEMBL22209506 | 0.84 | CCR1 (0.55) | TAAR1PREPACENPC1ELANE | |
| SCHEMBL18620675 | 0.84 | CMA1 (0.49) | CMA1TAAR1PREPGAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |