Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.69 |
| ▸ | DPP4 | P27487 | 2/20 | 0.69 |
| ▸ | FAP | Q12884 | 1/20 | 0.69 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 13/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209470 | 1.00 | PREP (0.69) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22468385 | 0.90 | NPC1 (0.61) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL28661857 | 0.90 | NPC1 (0.61) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22209433 | 0.88 | PREP (0.55) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL5313126 | 0.88 | DPP4 (0.55) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22811389 | 0.88 | PREP (0.55) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22811314 | 0.88 | PREP (0.55) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22811212 | 0.86 | DPP4 (0.56) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22209407 | 0.86 | DPP4 (0.62) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22811103 | 0.85 | ACE (0.54) | PREPDPP4FAPDPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |