Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368251 | 0.90 | CHRM4 (0.51) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18429064 | 0.88 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18428971 | 0.85 | CHRM4 (0.47) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18428975 | 0.85 | CHRM4 (0.47) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18429047 | 0.84 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18429063 | 0.83 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18429049 | 0.82 | CHRM4 (0.53) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL19273272 | 0.82 | CHRM4 (0.53) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL22813523 | 0.82 | CHRM4 (0.57) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18429022 | 0.81 | CHRM4 (0.52) | CHRM4CHRM2CHRM1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822262-A1 | MUSCARINIC AGONISTS | Heptares Therapeutics Limited (GB) | 2021-05-19 | — | — | EP | disclosed |
| EP-3331869-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2020-12-23 | — | — | EP | disclosed |