Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742457 | 1.00 | SLCO1B1 (0.41) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30472614 | 0.98 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22807077 | 0.92 | SLCO1B1 (0.47) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30205209 | 0.84 | SLCO1B1 (0.45) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL27224508 | 0.84 | SLCO1B1 (0.45) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30472580 | 0.84 | SLCO1B1 (0.41) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22817278 | 0.83 | SLCO1B1 (0.42) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22817291 | 0.83 | SLCO1B1 (0.42) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL28742445 | 0.83 | SLCO1B1 (0.42) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29645203 | 0.83 | SLCO1B1 (0.42) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257139-A1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-24 | — | — | WO | disclosed |