Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16048038 | 0.90 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16047863 | 0.81 | AOC3 (0.84) | AOC3KCNH2 | |
| SCHEMBL16049446 | 0.79 | KCNH2 (1.00) | AOC3KCNH2 | |
| SCHEMBL30025643 | 0.79 | KCNH2 (1.00) | AOC3KCNH2 | |
| SCHEMBL30026370 | 0.79 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL16049029 | 0.79 | AOC3 (1.00) | AOC3KCNH2 | |
| SCHEMBL20924524 | 0.76 | KCNH2 (0.79) | AOC3KCNH2 | |
| SCHEMBL16047677 | 0.75 | AOC3 (0.82) | AOC3KCNH2 | |
| SCHEMBL30026182 | 0.75 | AOC3 (0.82) | AOC3KCNH2 | |
| SCHEMBL16052839 | 0.74 | AOC3 (1.00) | AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200397764-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN, LLC | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200397764-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | VAPB, VAPA, OPRL1 | AOC3 55/4885KCNH2 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.